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Doctoral researcher in computational genomics for predictive medicine
利用多组学与机器学习研究疾病分子亚型
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The candidate profile is empty, so no qualifications, programming/research experience, or methodological fit can be assessed. Without evidence against the stated requirements, interview likelihood cannot be positively supported. Scores are therefore set to zero rather than inferred. · 迁移评估:unknown - candidate profile missing
软性注意
- 具备高性能计算或云环境经验者优先(非必需)
- 具备机器学习项目经验(如 PyTorch/TensorFlow)者优先(非必需)
- 具备医疗或基因组数据研究经验者优先(非必需)
- 具备小团队代码审查和版本控制经验者优先(非必需)
- 有使用 agentic AI 工具经验者优先(非必需)
数据完整(5/5),可生成高质量材料
PI 信息
主导师
Jeffrey C. Barrett
直接提取
院系
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
PI 近期论文(6 篇)
标记为「重要」或「很重要」的论文会进入 MV/CV 生成上下文;「一般」和「忽略」不进入。每次生成都读取最新标记。
[2024] Abstract 4146227: Combining metabolomic profiling with exome sequencing in the UK Biobank to predict cardiac outcomes and interpret variants of uncertain significance in familial hypercholesterolemia
通讯作者
[2024] Metabolomic profiling of the entire UK Biobank enables interpretation of familial hypercholesterolemia mutations and prediction of severe cardiovascular outcomes
第一作者
[2024] Associations of omega-3 fatty acid subclasses with cardiovascular diseases in 500,000 individuals
通讯作者
[2024] #2756 Metabolomic prediction of end stage renal disease in large national biobanks
第一作者
[2023] Abstract 18179: Metabolic Biomarker Signatures for Incident Heart Failure Hospitalisation Compared to Different Types of Cardiovascular Events: Evidence From NMR Metabolomics in 250,000 Individuals
通讯作者
[2021] Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon
通讯作者
手动添加论文 DOI
职位描述 / 要求
职位描述
Doctoral researcher in computational genomics for predictive medicine
The
Barrett lab at the University of Helsinki
is recruiting a doctoral researcher (PhD student) in computational genomics for predictive medicine. We are jointly affiliated with the
ELLIS Institute Finland
, the
Institute for Molecular Medicine Finland (FIMM)
, and the
Faculty of Medicine
at the University of Helsinki.
We analyze multiomic data to discover, understand, and measure mechanistically meaningful subtypes of complex human diseases. We believe that characterizing diseases not by their observed clinical phenotype, but by their molecular and biological endotype, will enable better treatment for patients. This long-held ambition in biomedicine is now poised to be realized due to:
• National research biobanks that collectively include millions of individuals with matched biosamples and detailed electronic health records.
• Large and growing multiomic data sets in samples from these biobanks, including genomics, proteomics, metabolomics, and transcriptomics.
• New machine learning and AI methods to build multiomic models that stratify disease risk, progression, and treatment response by molecular endotypes.
Find examples of research areas and possible projects on our website.
Responsibilities
• Design and implement a PhD research project on a topic related to computational genomics for predictive medicine.
• Carry out the research project: propose hypotheses, write code, think about and discuss results, and interpret findings.
• Collaborate closely with other members of the team, other researchers at the ELLIS Institute and University of Helsinki, and international partners.
• Share scientific results via publications and presentations at local and international conferences, and contribute more broadly to open science (e.g. via pre-prints and open source software).
• Contribute to mentoring and training the next generation of scientists.
Qualifications, experience, and skills
These items are most important for this role. We expect candidates to fulfill most of these:
• Motivation to work collaboratively on hard scientific problems with a pragmatic focus on getting things done.
• Master’s degree in computational biology, data science, bioinformatics, or a related discipline (exceptional candidates may be considered coming straight from a bachelor’s).
• Proficiency in programming for data analysis in either Python or R.
• Research experience in computational biology and/or data science.
• Excellent written and spoken English.
Any of the following are nice experience to have, but not essential. Please don’t be put off if you don’t have these:
• Working in high-performance or cloud compute environments.
• Working on machine learning problems (e.g. with frameworks such as PyTorch or TensorFlow).
• Research with health care and/or genomics data.
• Developing software in a small team environment with code review and version control.
• Using agentic AI tools (e.g. from Anthropic and OpenAI) while still retaining your own thinking process (see here for more about how we use AI).
What we offer
This is an opportunity to be one of the first members of a newly established laboratory led by Professor Jeffrey Barrett, who has over 20 years’ experience leading genomics research teams. You will benefit from hands-on supervision from Professor Barrett as well as active participation in the intellectual environments at both FIMM (genomics and molecular medicine) and the ELLIS Institute (fundamentals of applied AI).
Our team has access to biobank data sets which cumulatively include 2 million individuals (FinnGen, UK Biobank, All of Us, Estonian Biobank). We have access to both local supercomputer facilities as well as extensive cloud computing resources. We also routinely generate new ’omics data in samples available from the Finnish biobank network.
The position is for a fixed term, with a maximum duration of four years. A trial period of six months will be applied. The salary is based on the salary system of the
Finnish universities
. The starting salary is typically around 2600-2850 EUR per month, depending on the appointees’ qualifications and experience, and rises gradually as the PhD work progresses. The University of Helsinki offers comprehensive services to its employees, including occupational health care, support in access to high quality sports facilities, and many opportunities for professional development. Standard Finnish pension benefits are provided for university employees.
How to apply
Please submit your application through the University of Helsinki recruitment system by
November 19
, 2026. Your application should include:
• A one-page cover letter describing why you’re interested in this role. Please don’t use AI for this! It’s important to explain in your own voice.
• CV, including publications and github link if applicable
• Contact information for two references
For more information regarding the position or the research goals of the group, please contact Jeff at jeffrey.c.barrett(at)helsinki.fi.
More information
A diverse and equitable study and work culture is important to us. That is why we do our best to promote an inclusive university community. We encourage all qualified applicants from diverse backgrounds to apply for our positions.
Click this link to read about accessibility and inclusivity at our University.
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#HelsinkiUniCareers
The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalized medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki - a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.
ELLIS (European Laboratory for Learning and Intelligent Systems)
is a major European initiative in AI with a mission to strengthen Europe’s AI landscape by connecting top researchers, attracting talent, and fostering strategic collaborations. ELLIS unites leading machine learning researchers in Europe and operates as a multi-centric, pan-European AI Lab, currently spanning 47 research sites.
ELLIS Institute Finland was launched in 2025 and is
the second institute in the ELLIS network
, partnering with Finnish universities. We develop machine learning through fundamental research, with a particular focus on the fundamentals of applied AI: making machine learning more widely and effectively applicable, and better at working with people. AI for Research is one part of this focus.
Our faculty
works across a broad range of areas, including data-efficient probabilistic machine learning, generative modelling, amortized inference, interactive and cooperative machine learning, and transformative multidisciplinary collaboration. The institute will have a small number of strategic focus areas and the first one is AI for Health, spearheaded by a project to build a
nationwide foundation model
to support better decision-making in healthcare.
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Open position
Due Date:
19/11/2026
(23.59 Europe/Helsinki time)
Unit:
Helsinki Institute of Life Science
Sub-unit:
Institute for Molecular Medicine Finland (FIMM)
ID:
5268
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职位要求
These items are most important for this role. We expect candidates to fulfill most of these:
• Motivation to work collaboratively on hard scientific problems with a pragmatic focus on getting things done.
• Master’s degree in computational biology, data science, bioinformatics, or a related discipline (exceptional candidates may be considered coming straight from a bachelor’s).
• Proficiency in programming for data analysis in either Python or R.
• Research experience in computational biology and/or data science.
• Excellent written and spoken English.
申请材料(AI 定制)
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